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Xx male syndrome, also known as de la chapelle syndrome or 46,xx testicular disorder of sex development (or 46,xx dsd) is a rare intersex condition in which an individual with a 46,xx karyotype develops a male phenotype (2) xx males with ambiguity, usually detected at birth by external genital ambiguities such as. [2][3][4][5][6] in 90 percent of these individuals, the syndrome is caused by the father's y chromosome 's sry gene being atypically included in the crossing over of genetic.

Sex chromosomes are the genetic elements that define a person's biological sex (1) xx males with normal external or internal genitalia Learn about the xx and xy chromosomes, the sex determination system, and other chromosome combinations.

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What is the prognosis of xx male syndrome With hormonal replacement, therapy, surgery and multidisciplinary follow up the prognosis of xx male syndrome is good The patients can live a fairly normal life but like all disorders, they require a strong social support system, in the presence of which the quality of life is greatly improved. A rare disorder where individuals with two x chromosomes develop male characteristics due to sry gene translocation.

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