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You can have genetic abnormalities such as t (4;14) with any stage of a monoclonal gammopathy (mgus, smoldering multiple myeloma or symptomatic multiple myeloma). But it's only one risk factor, and, of course, each's person's disease is unique. The free light chain (flc) ratio at diagnosis can be a factor which increases risk of progression at diagnosis
I am mgus iga lambda and. My wife has igm myeloma, which is a rare case as i understand Didn't do we'll on biphosphates (jaw and dental issues) and my endo dr said i could be a candidate for another bone building drug that has steroids or hormones which could mask an m spike.
There are different models for risk of mgus progression out there from the mayo clinic, pethema, etc
Mgus with forehead lesion & collarbone bone growth by multibilly on wed oct 22, 2014 12:46 pm tennispro, Hello, last thursday i was diagnosed with smoldering myeloma I was diagnosed with smoldering mgus in mid 2013 By jan 2014 it became active and i did six months of chemo, then a stem cell harvest (no transplant)
I tried revlimid as a maintenance therapy but could not tolerate it Hi, my mum was given a diagnosis of mgus over 15 years ago and has had regular bloods and yearly bone marrow biopsies Interesting to hear about the relation between igm and neuropathy
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